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The problem was revisited this year 2010 when 18 senators wrote a letter to FDA commissioner Margaret Hamburg to let men who’ve sex with men donate blood. The FDA said at that right time that current science and data did not provide evidence for a policy reversal. While men who have sex with men just constitute 2 % of the populace, they make up 61 % of all new HIV infections in the U.S., the FDA reported. Approximately 77 % of diagnosed HIV infections among males could be traced to male-to-male sexual contact. The FDA highlights that others who have increased threat of HIV contamination including intravenous drug abusers, people who have received transplants from animal tissue or organs, those who have sex in exchange for money or drugs and folks who have traveled to or lived abroad in certain countries are also excluded.Second, GNA11 and the familial hypocalciuric hypercalcemia type 2 locus are colocalized on chromosome 19p13.3. This phenotype resembles neonatal severe primary hyperparathyroidism because of biallelic loss-of-function mutations in the calcium-sensing receptor.4,8 In autosomal dominant hypocalcemia type 1, about 50 percent of individuals have mild or asymptomatic hypocalcemia; about 50 percent possess paresthesia, carpopedal spasm, and seizures; about 10 percent possess hypercalciuria with nephrocalcinosis or kidney stones; and more than 35 percent have ectopic and basal ganglia calcifications .8,9 We performed GNA11 mutational analysis in a kindred with familial hypocalciuric hypercalcemia type 210,11 and in unrelated patients with familial hypocalciuric hypercalcemia who didn’t have CASR or AP2S1 mutations.1,5 We also performed this analysis in patients with hypocalcemia who didn’t have CASR mutations., and Desk S2 in the Supplementary Appendix).1,5,9,14 Informed consent was obtained from all people by using protocols approved by local and national ethics committees.