Related StoriesDiscovery could offer clues to how some infections control expression of genetic materialPresence of connexin proteins suppresses principal tumor growthStudy reveals system behind protein-related diseasesAC-100 dose dependently promoted cartilage fix in comparison to placebo. These results showing regular cartilage regeneration with AC-100 highly support our excitement because of this system, and we are looking towards initiating clinical trials in osteoarthritis and traumatic cartilage injury, said Dr.The association between a daily rest duration of five hours or less and coronary disease was strongest in adults under 60 years and in ladies . When topics with diabetes, hypertension or melancholy had been excluded from the evaluation, the association with cardiovascular disease remained high for sleep durations of five hours or less and nine hours or even more . Although individual sleep needs vary, the American Academy of Sleep Medicine recommends that most adults should obtain about seven to eight hours of nightly rest to feel alert and well rested during the day. According to the authors, the mechanisms underlying the association between brief sleep and cardiovascular disease can include sleep-related disturbances in endocrine and metabolic functions.